Von Willebrand disease - detection, diagnostics and treatment

von Willebrand disease is the most common inherited bleeding disorder, with mucocutaneous and menorrhagia as leading clinical manifestations. Cause of diathesis deficit or dysfunction vonWillebrand factor, plasma protein important roles in adhesion platelets to site vascular injury transport protection coagulation factor VIII. Prevalance disease, according different registries, between 1 on 100 persons 10000 persons. These data shows that detection disorder not easy many cases are undiagnosed. That why assessment tools developed they widely used for years. Confirmation diagnosis through laboratory testing. Some tests easily accessible. Therapy depends goals treatment (stopping bleeding, prophylaxis preoperative management). Last year, new guideline diagnostics was published by experts World Federation Haemophilia, International Society Thrombosis Haemostasis, American Hematology National Hemophilia Foundation. In this paper, recommendations detection, presented.